Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL13725826 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2432323 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10816938 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9100717 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2050659 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2304976 | 0.94 | — | — | |
| Bicarbonate SCHEMBL669862 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31116677 | 0.94 | — | — | |
| Bicarbonate SCHEMBL81419 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL19128 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122039246-A | High-flame-retardance nitrile-polyvinyl chloride composite fiber and preparation method thereof | 抚顺瑞华纤维有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-116589776-B | High-barrier light plastic and preparation method thereof | 界首市锦丰塑业有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-222816286-U | Liquid filtering type spray drying equipment for preparing magnesium aluminum carbonate | 台山市新宁制药有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-116459226-B | Aluminum magnesium carbonate double-layer tablet and preparation method thereof | 重庆康刻尔制药股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119843844-A | Construction process of joint-free bonded concrete terrace | 辽宁中和建筑装饰工程有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119752222-A | Interlayer perchlorate intercalation modification method for hydrotalcite | 安徽大学绿色产业创新研究院 | 2025-04-04 | — | — | CN | claimed |
| CN-119656122-A | Dapagliflozin and metformin sustained release tablet and preparation method thereof | 山东康美乐医药科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-222518269-U | Auxiliary agent mixing device for aluminum magnesium carbonate preparation | 太康海恩药业有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119480257-A | Polyvinyl chloride control cable | 广东汕沪电缆有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119424657-A | Application of aluminum magnesium carbonate and ursodeoxycholic acid oral suspension composition | 湖南一格制药有限公司 | 2025-02-14 | — | — | CN | claimed |
| EP-1542956-A1 | PROCESS FOR REDUCING FLUORIDE IMPURITIES RESULTING FROM USE OF FLUOROPHOSPHITE CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2005-06-22 | — | — | EP | claimed |
| WO-2004024662-A1 | PROCESS FOR REDUCING FLUORIDE IMPURITIES RESULTING FROM USE OF FLUOROPHOSPHITE CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2004-03-25 | — | — | WO | claimed |
| US-20040054211-A1 | Process for reducing fluoride impurities resulting from use of fluorophosphite catalysts | EASTMAN CHEMICAL COMPANY | 2004-03-18 | — | — | US | claimed |
| EP-0509864-B1 | Stabilized compositions of halogenated polymers containing a compound of lead or organo tin | RHONE POULENC CHIMIE (FR) | 1997-06-25 | — | — | EP | claimed |
| US-5480587-A | PAPER OR POLYMERS | ALUMINUM COMPANY OF AMERICA (US) | 1996-01-02 | — | — | US | claimed |
| EP-0275574-B1 | Polyamide composition | DSM NV (NL) | 1994-01-26 | — | — | EP | claimed |
| EP-0151736-B1 | HIGH DENSITY INFORMATION RECORDS MADE OF CONDUCTIVE RESIN COMPOSITIONS COMPRISING INORGANIC POWDER STABILIZERS | VICTOR COMPANY OF JAPAN, LIMITED (JP) | 1989-03-22 | — | — | EP | claimed |
| EP-0275574-A1 | Polyamide composition | DSM N.V. (NL) | 1988-07-27 | — | — | EP | claimed |
| EP-0117289-B1 | BASIC MAGNESIUM-ALUMINIUM-HYDROXYCARBONATE | Giulini Chemie GmbH (DE) | 1988-06-29 | — | — | EP | claimed |
| US-4447417-A | ANTACIDS; GASTROINTESTINAL DISORDERS | ANPHAR S.A. (ES) | 1984-05-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054211-A1 | Process for reducing fluoride impurities resulting from use of fluorophosphite catalysts | PPIP5K2, PFAS, NSF | CA4 548/4885CA1 1282/4885FAHD1 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.