Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101086 | 0.99 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1LTB4RNOTUM | |
| SCHEMBL7100819 | 0.90 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1 | |
| SCHEMBL7101124 | 0.87 | F13A1 (0.39) | LTB4RF13A1RXFP1ALDH1A1LMNA | |
| SCHEMBL6708361 | 0.85 | HPGD (0.38) | CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1 | |
| SCHEMBL7096431 | 0.85 | KDM4E (0.46) | RXFP1ALDH1A1LMNAPRNPRECQL | |
| SCHEMBL7102424 | 0.84 | ALDH1A1 (0.47) | RXFP1ALDH1A1LMNAPRNPRECQL | |
| SCHEMBL6709557 | 0.81 | KAT2B (0.36) | CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1 | |
| SCHEMBL6708455 | 0.79 | RPS6KB2 (0.37) | CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1 | |
| SCHEMBL7100139 | 0.76 | KDM4E (0.48) | CSNK2A2CSNK2BCSNK2A1NOTUMALDH1A1 | |
| SCHEMBL6711488 | 0.75 | ACHE (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355649-A2 | PHARMACEUTICAL FORMULATION CONTAINING PYRAZOLO 4,3-D]PYRIMIDINE AND NITRATES OR THIENOPYRIMIDINES AND NITRATES | MERCK PATENT GmbH (DE) | 2003-10-29 | — | — | EP | disclosed |
| EP-1347761-A2 | PHARMACEUTICAL FORMULATION CONTAINING THIENOPYRIMIDINES AND ANTITHROMBOTICS, CALCIUM ANTAGONISTS, PROSTAGLANDINS OR PROSTAGLANDIN DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-01 | — | — | EP | disclosed |
| EP-1337256-A2 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002060449-A2 | PHARMACEUTICAL FORMULATION CONTAINING PYRAZOLO[4,3-D]PYRIMIDINE AND NITRATES OR THIENOPYRIMIDINES AND NITRATES | MERCK PATENT GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |
| WO-2002049650-A2 | PHARMACEUTICAL FORMULATION CONTAINING THIENOPYRIMIDINES AND ANTITHROMBOTICS, CALCIUM ANTAGONISTS, PROSTAGLANDINS OR PROSTAGLANDIN DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002041896-A2 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2002-05-30 | — | — | WO | disclosed |
| EP-1036078-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028325-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1999-06-10 | — | — | WO | disclosed |