⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17253261 | 0.87 | ALDH1A1 (0.50) | — | |
| SCHEMBL1104791 | 0.80 | — | — | |
| SCHEMBL16327847 | 0.79 | ALDH1A1 (0.48) | — | |
| SCHEMBL4343290 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL12109957 | 0.79 | ALDH1A1 (0.54) | — | |
| SCHEMBL12103657 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL1040128 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL16441931 | 0.79 | THRB (0.50) | — | |
| SCHEMBL12103912 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL16256310 | 0.77 | TSHR (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771613-B2 | Methods and apparatus for synthesizing nucleic acid | Molecular Assemblies, Inc. (US) | 2017-09-26 | — | — | US | disclosed |
| US-9695470-B2 | Methods and apparatus for synthesizing nucleic acids | Molecular Assemblies, Inc. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20160361432-A1 | CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS | ENDOCYTE INC (IN) | 2016-12-15 | — | — | US | disclosed |
| US-20160168611-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS | Molecular Assemblies, Inc. | 2016-06-16 | — | — | US | disclosed |
| US-9279149-B2 | Methods and apparatus for synthesizing nucleic acids | Molecular Assemblies, Inc. (US) | 2016-03-08 | — | — | US | disclosed |
| US-20160046973-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACID | Molecular Assemblies, Inc. | 2016-02-18 | — | — | US | disclosed |
| US-20160046974-A1 | REUSABLE INITIATORS FOR SYNTHESIZING NUCLEIC ACIDS | Molecular Assemblies, Inc. | 2016-02-18 | — | — | US | disclosed |
| US-20140363852-A1 | METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS | Molecular Assemblies, Inc. | 2014-12-11 | — | — | US | disclosed |
| US-20030220524-A1 | Sulfur containing compounds | LANGLER RICHARD FRANCIS (CA) | 2003-11-27 | — | — | US | disclosed |
| EP-1259482-A2 | SULFUR CONTAINING COMPOUNDS | University Health Network (CA) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062668-A2 | SULFUR CONTAINING COMPOUNDS | UNIVERSITY HEALTH NETWORK (CA) | 2001-08-30 | — | — | WO | disclosed |