Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111154 | 0.83 | TP53 (0.39) | — | |
| SCHEMBL7113956 | 0.78 | TLR7 (0.40) | PDE3BPDE3AARTLR7 | |
| SCHEMBL687471 | 0.77 | POLB (0.47) | — | |
| SCHEMBL7113832 | 0.76 | PDE3B (0.35) | PDE3BPDE3A | |
| SCHEMBL7110018 | 0.75 | PDE3B (0.36) | PDE3BPDE3AAR | |
| SCHEMBL27836346 | 0.75 | SOS1 (0.43) | — | |
| SCHEMBL8172740 | 0.73 | ALDH1A1 (0.53) | — | |
| SCHEMBL7112341 | 0.72 | PDE3B (0.38) | PDE3BPDE3AARTLR7 | |
| SCHEMBL2209235 | 0.72 | SLC22A12 (0.43) | — | |
| SCHEMBL2103829 | 0.72 | NR4A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351924-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002050019-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA CO. (US) | 2002-06-27 | — | — | WO | disclosed |