Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110018 | 0.86 | PDE3B (0.36) | PDE3BPDE3AAR | |
| SCHEMBL7113956 | 0.79 | TLR7 (0.40) | PDE3BPDE3AARTLR7IDO1 | |
| SCHEMBL7447385 | 0.77 | IDO1 (0.35) | IDO1TRPA1 | |
| SCHEMBL6236003 | 0.75 | POLB (0.50) | PDE3BPDE3AARTLR7PTPN1 | |
| SCHEMBL7111154 | 0.74 | TP53 (0.39) | ALDH1A1CYP1A2POLB | |
| SCHEMBL7113832 | 0.74 | PDE3B (0.35) | PDE3BPDE3AIDO1 | |
| SCHEMBL2209235 | 0.73 | SLC22A12 (0.43) | CYP1A2 | |
| SCHEMBL5217967 | 0.73 | KMT2A (0.42) | ALDH1A1CYP1A2POLB | |
| SCHEMBL7112683 | 0.72 | PDE3B (0.36) | PDE3BPDE3AARTLR7 | |
| SCHEMBL687401 | 0.72 | POLB (0.45) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351924-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002050019-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA CO. (US) | 2002-06-27 | — | — | WO | disclosed |