Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.30 |
| ▸ | PPARG | P37231 | 7/20 | 0.30 |
| ▸ | PPARD | Q03181 | 7/20 | 0.30 |
| ▸ | PPARA | Q07869 | 7/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FABP4 | P15090 | 2/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333181 | 0.87 | TBXAS1 (0.31) | TBXAS1TSHRLMNANFKB1PMP22 | |
| SCHEMBL38826 | 0.79 | PPARG (0.35) | TSHRGPR84PPARGPPARDPPARA | |
| SCHEMBL9230299 | 0.78 | TSHR (0.30) | TSHRNFKB1 | |
| SCHEMBL11173428 | 0.77 | — | — | |
| SCHEMBL3853180 | 0.76 | — | — | |
| SCHEMBL4339507 | 0.76 | TSHR (0.31) | TSHRNFKB1 | |
| SCHEMBL316765 | 0.76 | TSHR (0.34) | TBXAS1TSHRLMNANFKB1PMP22 | |
| SCHEMBL5448887 | 0.76 | TSHR (0.34) | TBXAS1TSHRLMNANFKB1PMP22 | |
| SCHEMBL5453694 | 0.76 | TSHR (0.34) | TBXAS1TSHRLMNANFKB1PMP22 | |
| SCHEMBL5450327 | 0.76 | TSHR (0.34) | TBXAS1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638997-B2 | Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-28 | — | — | US | disclosed |
| US-6420463-B1 | HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORP. | 2002-07-16 | — | — | US | disclosed |
| EP-0912471-A1 | POLYMERISATION INHIBITOR | A.H. Marks & Co. Limited (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998002400-A1 | POLYMERISATION INHIBITOR | A.H. MARKS AND COMPANY LIMITED (GB) | 1998-01-22 | — | — | WO | disclosed |