SCHEMBL333181

SCHEMBL333181

CN1C(C)(C)CCC(C(CCCCCCCC(=O)O)(C(=O)O)C2CCC(C)(C)N(C)C2(C)C)C1(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.31
TSHR P16473 5/20 0.31
LMNA P02545 1/20 0.31
NFKB1 P19838 1/20 0.31
PMP22 Q01453 1/20 0.31
ITGB3 P05106 1/20 0.30
ITGA2B P08514 1/20 0.30
GPR84 Q9NQS5 7/20 0.30
PPARG P37231 7/20 0.30
PPARD Q03181 7/20 0.30
PPARA Q07869 7/20 0.30
HDAC11 Q96DB2 5/20 0.30
PTPN1 P18031 3/20 0.30
ALDH1A1 P00352 2/20 0.30
TLR2 O60603 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
FABP4 P15090 2/20 0.30
SLC22A6 Q4U2R8 1/20 0.30
SLC22A8 Q8TCC7 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4339507 0.89 TSHR (0.31) TSHRNFKB1
SCHEMBL9230299 0.89 TSHR (0.30) TSHRNFKB1
SCHEMBL3853180 0.87
SCHEMBL7113191 0.87 TBXAS1 (0.31) TBXAS1TSHRLMNANFKB1PMP22
SCHEMBL14480710 0.86 TBXAS1 (0.33) TBXAS1TSHRLMNANFKB1PMP22
SCHEMBL4334133 0.81 TSHR (0.33) TSHRNFKB1
SCHEMBL9799359 0.79 VCAM1 (0.32)
SCHEMBL38826 0.79 PPARG (0.35) TSHRGPR84PPARGPPARDPPARA
SCHEMBL11173428 0.77
Sebacic Acid SCHEMBL28467106 0.76 TSHR (0.38) TSHRLMNANFKB1PMP22ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828245-A1 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS Honeywell International Inc. (US) 2021-06-02 EP claimed
EP-3491095-A2 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS Honeywell International Inc. (US) 2019-06-05 EP claimed
EP-3491094-A1 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS Honeywell International Inc. (US) 2019-06-05 EP claimed
EP-3365408-A1 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS Honeywell International Inc. (US) 2018-08-29 EP claimed
WO-2018022943-A1 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS HONEYWELL INTERNATIONAL INC. (US) 2018-02-01 WO claimed
WO-2018022888-A1 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS HONEYWELL INTERNATIONAL INC. (US) 2018-02-01 WO claimed
WO-2018022949-A2 HEAT TRANSFER COMPOSITIONS, METHODS AND SYSTEMS HONEYWELL INTERNATIONAL INC. (US) 2018-02-01 WO claimed
EP-1885787-B1 PHOSPHITE ADDITIVES IN POLYOLEFINS PHILLIPS PETROLEUM CO (US) 2018-01-10 EP claimed
US-9777204-B2 Epoxide and fluorinated epoxide stabilizers for fluoroolefins THE CHEMOURS COMPANY FC, LLC (US) 2017-10-03 US claimed
US-8496846-B2 Phenol stabilizers for fluoroolefins E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-30 US claimed
US-8383004-B2 Amine stabilizers for fluoroolefins E I DU PONT DE NEMOURS AND COMPANY (US) 2013-02-26 US claimed
US-20120047925-A1 PHENOL STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-01 US claimed
US-8101094-B2 Terpene, terpenoid, and fullerene stabilizers for fluoroolefins E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-24 US claimed
US-20110259022-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY 2011-10-27 US claimed
US-20110041530-A1 AMINE STABILIZERS FOR FLUOROOLEFINS E. I. DUPONT DE NEMOURS AND COMPANY (US) 2011-02-24 US claimed
US-7157511-B2 Phosphite additives in polyolefins CHEVRON PHILLIPSCHEMICAL COMPANY LP 2007-01-02 US claimed
US-20050113494-A1 Phosphite additives in polyolefins THE HUNTINGTON NATIONAL BANK 2005-05-26 US claimed
US-4965301-A STABILIZERS COMPRISING A HINDERED PHENOL, ORGANIC PHOSPHITE, A HINDERED AMINE, A METAL SOAP AND TRISODIUM PHOSPATE; HEAT RESISTANCE FOR MELT SPUN FINISHED FIBERS PHILLIPS PETROLEUM COMPANY (US) 1990-10-23 US claimed
US-4730015-A BENZOTRIAZOLE AND PIPERIDINE STABILIZER POLYPLASTICS CO., LTD. (JP) 1988-03-08 US claimed
EP-0184191-A2 Stabilization of polyolefins PHILLIPS PETROLEUM COMPANY (US) 1986-06-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110041530-A1 AMINE STABILIZERS FOR FLUOROOLEFINS AFF1, PFAS, FLNA TBXAS1 1087/4885TSHR 1762/4885LMNA 4197/4885
US-20120047925-A1 PHENOL STABILIZERS FOR FLUOROOLEFINS HSF1, FLOT1, FOXK1 TBXAS1 1715/4885TSHR 2710/4885LMNA 3938/4885
US-20110259022-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS PFAS, OXER1, FLOT1 TBXAS1 442/4885TSHR 2953/4885LMNA 4266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.