SCHEMBL7113258

SCHEMBL7113258

C[Si](C)(O[Si](C)(C)C1CC2C=CC1C2)C1CC2C=CC1C2

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23573080 0.92
SCHEMBL2605526 0.92
SCHEMBL6745893 0.87
SCHEMBL6783803 0.87 KDM4E (0.30) KDM4ELMNA
SCHEMBL23499904 0.85 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL200055 0.85 KDM4E (0.30) KDM4EALDH1A1
SCHEMBL18571585 0.83
SCHEMBL6743756 0.82 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL2605522 0.81 KDM4E (0.30) KDM4EALDH1A1
SCHEMBL14012991 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030208016-A1 Radical polymerizable compositions containing polycyclic olefins HENKEL LOCTITE CORPORATION 2003-11-06 US claimed
EP-3565850-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2025-07-23 EP disclosed
US-20250122402-A1 LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS PROMERUS, LLC (US) 2025-04-17 US disclosed
US-11897991-B2 UV active derivatives of Pd(AcAc)2 catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2024-02-13 US disclosed
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PROMERUS, LLC (US) 2023-09-19 US disclosed
US-11746166-B2 UV active derivatives of pd(AcAc)2L catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-09-05 US disclosed
US-20230266668-A1 DUAL CATALYST SYSTEM FOR MASS ROMP AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 US disclosed
US-20230265243-A1 DUAL CATALYST SYSTEM FOR MASS VINYL ADDITION AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 US disclosed
US-20230220132-A1 FAST PHOTOCURABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL OR 3D PRINTING MATERIALS PROMERUS, LLC (US) 2023-07-13 US disclosed
US-11639405-B2 Fast photocurable polycycloolefin compositions as optical or 3D printing materials PROMERUS, LLC (US) 2023-05-02 US disclosed
US-20030208016-A1 Radical polymerizable compositions containing polycyclic olefins HENKEL LOCTITE CORPORATION 2003-11-06 US disclosed
US-6521731-B2 For use in electronics, CD-ROM disks, optical lenses, barrier films, and medical appliances HENKEL LOCTITE CORPORATION 2003-02-18 US disclosed
US-20030008992-A1 Radical polymerizable compositions containing polycyclic olefins Henkel IP & Holding GmbH (DE) 2003-01-09 US disclosed
WO-2002062859-A2 RADICAL POLYMERIZABLE COMPOSITIONS CONTAINING POLYCYCLIC OLEFINS LOCTITE (US) 2002-08-15 WO disclosed
EP-0940405-B1 Organosilicon compounds containing alkenyl groups WACKER CHEMIE GMBH (DE) 2002-03-13 EP disclosed
US-6252101-B1 ADDITION-CONDENSATION POLYMER WACKER-CHEMIE GMBH (DE) 2001-06-26 US disclosed
EP-0940405-A1 Organosilicon compounds containing alkenyl groups Wacker-Chemie GmbH (DE) 1999-09-08 EP disclosed
EP-0601008-B1 PROCESS FOR PRODUCING EPOXY GROUPS-CONTAINING ORGANOSILICIUM COMPOUNDS WACKER CHEMIE GMBH (DE) 1995-11-22 EP disclosed
EP-0601008-A1 PROCESS FOR PRODUCING EPOXY GROUPS-CONTAINING ORGANOSILICIUM COMPOUNDS. WAKKER CHEMIE GMBH (DE) 1994-06-15 EP disclosed
WO-1993005051-A1 PROCESS FOR PRODUCING EPOXY GROUPS-CONTAINING ORGANOSILICIUM COMPOUNDS WACKER-CHEMIE GMBH (DE) 1993-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PPOX, VCL, PFN1 KDM4E 3000/4885ALDH1A1 2726/4885LMNA 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.