SCHEMBL711336

SCHEMBL711336

C[Si](C)(C)O[Si](C)(O[Si](C)(C)C)O[Si](CCC[CH]C(O)CO)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373856 0.93
SCHEMBL373574 0.80
SCHEMBL373470 0.80
SCHEMBL2367736 0.75
SCHEMBL30623396 0.73
SCHEMBL373636 0.73 AKR1B1 (0.33)
SCHEMBL711337 0.72 USP2 (0.46)
SCHEMBL30623393 0.70 LMNA (0.32)
SCHEMBL1802297 0.69 TBXAS1 (0.31)
SCHEMBL6658625 0.68 AKR1B1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657751-B1 Soft ocular lens material MENICON CO LTD (JP) 2003-04-23 EP claimed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
WO-2023068316-A1 MATERIAL FOR SOFT CONTACT LENS HAVING CONTRAST IMPROVEMENT FUNCTION 興和株式会社 2023-04-27 WO disclosed
US-20220213050-A1 CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE TOKUYAMA CORPORATION (JP) 2022-07-07 US disclosed
US-20180356561-A1 GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER JSR CORPORATION (JP) 2018-12-13 US disclosed
EP-2857459-B1 STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS KOWA CO (JP) 2017-12-27 EP disclosed
EP-2330161-B1 DYE COMPOSITION FOR OPHTHALMIC LENS, METHOD FOR PRODUCING COLORED OPHTHALMIC LENS USING THE SAME AND COLORED OPHTHALMIC LENS MENICON CO LTD (JP) 2017-01-25 EP disclosed
US-9365501-B2 Stable polymerizable UV-absorbing colorant for intraocular lens KOWA COMPANY, LTD. (JP) 2016-06-14 US disclosed
US-9017716-B2 Ophthalmic lens MENICON CO., LTD. (JP) 2015-04-28 US disclosed
EP-2857459-A1 STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS Kowa Company Ltd. (JP) 2015-04-08 EP disclosed
US-20150094439-A1 STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS KOWA COMPANY, LTD. (JP) 2015-04-02 US disclosed
EP-0657751-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1995-06-14 EP disclosed
EP-0379146-B1 Soft ocular lens material MENICON CO LTD (JP) 1995-05-17 EP disclosed
US-5416180-A Fluorine containing (meth)acrylate polymers MENICON CO., LTD. (JP) 1995-05-16 US disclosed
EP-0381005-B1 Ocular lens material MENICON CO LTD (JP) 1995-01-11 EP disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed
EP-0578087-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-01-12 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
US-4954586-A COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE MENICON CO., LTD (JP) 1990-09-04 US disclosed
EP-0379146-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1990-07-25 EP disclosed