Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.51 |
| ▸ | NPY1R | P25929 | 6/20 | 0.51 |
| ▸ | NPY2R | P49146 | 4/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113436 | 1.00 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5ROPRD1 | |
| SCHEMBL7872640 | 0.92 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7872647 | 0.92 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7867783 | 0.91 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22133174 | 0.91 | NPY4R (0.57) | NPY4RNPY1RNPY2RNPY5ROPRL1 | |
| SCHEMBL7867797 | 0.91 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13448837 | 0.89 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30437446 | 0.89 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29568941 | 0.89 | OPRL1 (0.50) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL30903436 | 0.88 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5ROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358342-A2 | RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM | The Children's Medical Center Corporation (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059338-A2 | RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |
| US-6303116-B1 | CAPABLE OF TRANSDUCING THERAPEUTIC GENES INTO NON-DIVIDING CELLS. | THOMAS JEFFERSON UNIVERSITY | 2001-10-16 | — | — | US | disclosed |