Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CCKAR | P32238 | 3/20 | 0.51 |
| ▸ | CCKBR | P32239 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872647 | 1.00 | OPRD1 (0.56) | OPRD1OPRM1OPRK1MMP2CCKAR | |
| SCHEMBL7113442 | 0.92 | NPY4R (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7113436 | 0.92 | NPY4R (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29590137 | 0.91 | MMP2 (0.58) | OPRK1MMP2 | |
| SCHEMBL29531641 | 0.91 | MMP2 (0.58) | OPRK1MMP2 | |
| SCHEMBL7592267 | 0.89 | OPRD1 (0.49) | OPRD1OPRM1OPRK1MMP2 | |
| SCHEMBL7592268 | 0.89 | OPRD1 (0.49) | OPRD1OPRM1OPRK1MMP2 | |
| SCHEMBL1374173 | 0.88 | OPRD1 (0.59) | OPRD1OPRM1OPRK1CCKARCCKBR | |
| SCHEMBL30977978 | 0.88 | OPRK1 (0.55) | OPRK1MMP2 | |
| SCHEMBL1371635 | 0.88 | MMP2 (0.55) | OPRD1OPRM1OPRK1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303116-B1 | CAPABLE OF TRANSDUCING THERAPEUTIC GENES INTO NON-DIVIDING CELLS. | THOMAS JEFFERSON UNIVERSITY | 2001-10-16 | — | — | US | disclosed |