Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.31 |
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7110419 | 1.00 | MMP2 (0.31) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL15284747 | 0.89 | KMT2A (0.30) | — | |
| SCHEMBL4074103 | 0.89 | KMT2A (0.30) | — | |
| SCHEMBL8520957 | 0.89 | KMT2A (0.30) | — | |
| SCHEMBL3345612 | 0.87 | — | — | |
| SCHEMBL27734262 | 0.80 | — | — | |
| SCHEMBL15984941 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL28774892 | 0.78 | TSHR (0.32) | MMP2FDPSMMP1MMP3 | |
| Phosphoric Acid SCHEMBL28017885 | 0.78 | TSHR (0.32) | MMP2FDPSMMP1MMP3 | |
| Phosphoric Acid SCHEMBL15334183 | 0.78 | TSHR (0.32) | MMP2FDPSMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195364-B1 | Hydraulic cement compositions and additives therefore | TAKEMOTO OIL & FAT CO LTD (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-6454849-B1 | MIXTURES OF HYDROXYETHER, PHOSPHORIC ESTER AND ANTIFOAM AGENT | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2002-09-24 | — | — | US | disclosed |
| EP-1195364-A2 | Hydraulic cement compositions and additives therefore | Takemoto Yushi Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |