Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29284258 | 0.90 | TSHR (0.48) | TSHREP300TP53 | |
| SCHEMBL11601333 | 0.90 | TSHR (0.44) | TSHRALDH1A1EP300TP53HPGD | |
| SCHEMBL108398 | 0.90 | TSHR (0.44) | TSHRALDH1A1EP300TP53HPGD | |
| SCHEMBL108399 | 0.90 | TSHR (0.44) | TSHRALDH1A1EP300TP53HPGD | |
| SCHEMBL9856471 | 0.87 | TSHR (0.46) | TSHRALDH1A1EP300HPGD | |
| SCHEMBL9856475 | 0.87 | TSHR (0.46) | TSHRALDH1A1EP300HPGD | |
| SCHEMBL29284448 | 0.86 | TSHR (0.48) | TSHREP300TP53 | |
| SCHEMBL8430984 | 0.85 | TSHR (0.39) | TSHRALDH1A1TP53HPGDCES2 | |
| SCHEMBL8430987 | 0.85 | TSHR (0.39) | TSHRALDH1A1TP53HPGDCES2 | |
| SCHEMBL2879170 | 0.82 | TSHR (0.39) | TSHRALDH1A1TP53CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525140-B1 | Method of preparation of coupled branched and linear polymer compositions | FIRESTONE POLYMERS, LLC | 2003-02-25 | — | — | US | disclosed |