SCHEMBL711464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL712557	0.87	AGXT (0.33)	AGXTAPPCA2CYP2C9
	SCHEMBL713791	0.83	BRS3 (0.44)	CYP2C9
	SCHEMBL713329	0.83	AGXT (0.36)	AGXTAPPPDE10AATP4AATP4B
	SCHEMBL712047	0.81	APP (0.38)	AGXTAPPPDE10AATP4AATP4B
	SCHEMBL712121	0.81	APP (0.38)	AGXTAPPPDE10AATP4AATP4B
	Water SCHEMBL713364	0.80	APP (0.37)	AGXTAPPPDE10AATP4AATP4B
	SCHEMBL3176688	0.74	AGXT (0.34)	AGXTPDE10A
	SCHEMBL714517	0.71	PDE10A (0.36)	AGXTPDE10AATP4AATP4B
	SCHEMBL263387	0.70	CA2 (0.45)	APPCA2
	SCHEMBL13358775	0.70	KMT2A (0.42)	CYP2C9ATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.