SCHEMBL712557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL711464	0.87	AGXT (0.35)	AGXTAPPCYP2C9CA2
	SCHEMBL713329	0.80	AGXT (0.36)	AGXTAPP
	SCHEMBL712047	0.78	APP (0.38)	AGXTAPP
	SCHEMBL1846086	0.77	CYP2D6 (0.38)	APPALDH1A1CYP3A4CYP2D6TSHR
	Water SCHEMBL713364	0.77	APP (0.37)	AGXTAPPKMT2A
	SCHEMBL713791	0.73	BRS3 (0.44)	ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL562062	0.69	CA2 (0.58)	ALDH1A1CYP3A4CYP2D6TSHRCYP2C9
	SCHEMBL898388	0.69	CA2 (0.58)	ALDH1A1CYP3A4CYP2D6TSHRCYP2C9
	SCHEMBL411517	0.69	CA2 (0.58)	ALDH1A1CYP3A4CYP2D6TSHRCYP2C9
	SCHEMBL4492348	0.69	ATP4A (0.31)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.