Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858946 | 0.85 | CTSA (0.44) | ACHECTSAALDH1A1CYP3A4MAOB | |
| SCHEMBL7112710 | 0.75 | CYP2D6 (0.49) | ALDH1A1CYP3A4SYKMEN1CYP2C9 | |
| SCHEMBL3857605 | 0.73 | ACHE (0.58) | ACHEALDH1A1CYP3A4MEN1USP2 | |
| SCHEMBL18763605 | 0.72 | ACHE (0.52) | ACHECTSAALDH1A1CYP3A4MAOB | |
| SCHEMBL14003414 | 0.70 | MAOB (0.52) | ACHEALDH1A1MAOBPOLBMAPT | |
| SCHEMBL13932512 | 0.70 | ACHE (0.54) | ACHEALDH1A1MAOBALKBH3SYK | |
| SCHEMBL14003492 | 0.70 | ACHE (0.65) | ACHEALDH1A1CYP3A4MAOBMAOA | |
| SCHEMBL27704500 | 0.69 | SMPD3 (0.46) | ACHE | |
| SCHEMBL14446041 | 0.69 | ACHE (0.58) | ACHEALDH1A1CYP3A4MAOBMAOA | |
| SCHEMBL139182 | 0.68 | ESRRA (0.46) | ALDH1A1MAOBMAOAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638646-B2 | Polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | SEMICONDUCTORS GMBH (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030088050-A1 | Substituted poly(arylenevinylenes), process for their preparation, and their use in electroluminescent elements | MERCK PATENT GMBH (DE) | 2003-05-08 | — | — | US | disclosed |
| US-20020064680-A1 | Substituted poly(arylene vinylenes), method for producing the same, and their use in electroluminescent elements | AXIVA GMBH (DE) | 2002-05-30 | — | — | US | disclosed |