Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445989 | 1.00 | ESRRA (0.46) | ESRRAALDH1A1TDP1S1PR4MEN1 | |
| SCHEMBL1046094 | 0.95 | ESRRA (0.46) | ESRRAALDH1A1TDP1S1PR4MEN1 | |
| SCHEMBL10110954 | 0.87 | CYP46A1 (0.46) | ESRRAALDH1A1MEN1KMT2A | |
| SCHEMBL10110943 | 0.86 | ESRRA (0.41) | ESRRAALDH1A1TDP1S1PR4MEN1 | |
| SCHEMBL15435579 | 0.86 | ESRRA (0.41) | ESRRAALDH1A1TDP1S1PR4MEN1 | |
| SCHEMBL2095900 | 0.86 | ESRRA (0.41) | ESRRAALDH1A1TDP1S1PR4MEN1 | |
| SCHEMBL2784444 | 0.86 | ACHE (0.50) | ESRRAALDH1A1TDP1HPGDMAOB | |
| SCHEMBL5280419 | 0.86 | AHR (0.42) | ESRRAALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL29637921 | 0.86 | ESRRA (0.61) | ESRRAALDH1A1TDP1MAOBCYP1A2 | |
| SCHEMBL27887044 | 0.86 | ACHE (0.50) | ESRRAMEN1HPGDKMT2AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6538725-B2 | Method for determination of structural defects of coatings | GENERAL ELECTRIC COMPANY | 2003-03-25 | — | — | US | claimed |
| US-20020135758-A1 | Method for determination of structural defects of coatings | GENERAL ELECTRIC COMPANY | 2002-09-26 | — | — | US | claimed |
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-8841134-B2 | Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications | BRUKER BIOSPIN CORPORATION (US) | 2014-09-23 | — | — | US | disclosed |
| US-8834846-B2 | Fluorescent NIRF activatable probes for disease detection | BRUKER BIOSPIN CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | BRUKER BIOSPIN CORPORATION | 2011-12-01 | — | — | US | disclosed |
| EP-2004713-B1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES | CARESTREAM HEALTH INC (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | QUANTUM MEDICAL HOLDINGS, LLC | 2010-02-11 | — | — | US | disclosed |
| US-20090169482-A1 | SILICA-CORED CARRIER PARTICLE | QUANTUM MEDICAL HOLDINGS, LLC | 2009-07-02 | — | — | US | disclosed |
| US-20090098057-A1 | SILICA-CORED CARRIER PARTICLE | QUANTUM MEDICAL IMAGING, L.L.C. | 2009-04-16 | — | — | US | disclosed |
| US-6538725-B2 | Method for determination of structural defects of coatings | GENERAL ELECTRIC COMPANY | 2003-03-25 | — | — | US | disclosed |
| US-20030038941-A1 | Method for the rapid determination of the optical quality of combinatorial libraries | GENERAL ELECTRIC COMPANY | 2003-02-27 | — | — | US | disclosed |
| US-20030021998-A1 | TAGGING MATERIALS FOR POLYMERS, METHODS, AND ARTICLES MADE THEREBY | CITIBANK, N.A., AS COLLATERAL AGENT | 2003-01-30 | — | — | US | disclosed |
| US-6499355-B1 | Elongation and cracking testing and optical characterization of small-size coatings and materials | GENERAL ELECTRIC COMPANY | 2002-12-31 | — | — | US | disclosed |
| US-6460417-B1 | Formability testing of small-size coatings and materials | GENERAL ELECTRIC COMPANY | 2002-10-08 | — | — | US | disclosed |
| US-20020135758-A1 | Method for determination of structural defects of coatings | GENERAL ELECTRIC COMPANY | 2002-09-26 | — | — | US | disclosed |
| EP-0596098-B1 | FLUORESCENT MICROPARTICLES WITH CONTROLLABLE ENHANCED STOKES SHIFT | MOLECULAR PROBES INC (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5573909-A | DETECTING MULTIPLE DIFFERENT TARGET SPECIFIC BINDING PAIR MEMBER IN SAMPLE BY USING PROBES COMPRISING POLYMERIC MICROPARTICLE CONTAINING DISPERSED SERIES OF FLUORESCENT DYES, AND COMPLEMENTARY SPECIFIC BINDING PAIR MEMBER | MOLECULAR PROBES, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5326692-A | Polyazaindacene dyes | MOLECULAR PROBES, INC. (US) | 1994-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | CLTA, COPE, CD68 | ESRRA 3789/4885ALDH1A1 2203/4885TDP1 987/4885 |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | LASP1, LSS, SELL | ESRRA 4296/4885ALDH1A1 1094/4885TDP1 1705/4885 |
| US-20090098057-A1 | SILICA-CORED CARRIER PARTICLE | MSN, CD44, SND1 | ESRRA 2910/4885ALDH1A1 4020/4885TDP1 3558/4885 |
| US-20090169482-A1 | SILICA-CORED CARRIER PARTICLE | MSN, CD44, SND1 | ESRRA 2910/4885ALDH1A1 4020/4885TDP1 3558/4885 |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | CTSF, ENGASE, DNTT | ESRRA 4056/4885ALDH1A1 754/4885TDP1 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.