Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799154 | 1.00 | LMNA (0.53) | LMNAATMALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11538425 | 0.98 | ATM (0.53) | LMNAATMALDH1A1MEN1KMT2A | |
| SCHEMBL2084284 | 0.98 | ATM (0.51) | LMNAATMALDH1A1MEN1KMT2A | |
| SCHEMBL2227656 | 0.81 | PHGDH (0.71) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9189792 | 0.81 | PHGDH (0.49) | LMNAALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL6801446 | 0.81 | MAPT (0.55) | ALDH1A1MEN1KMT2AL3MBTL1PHGDH | |
| SCHEMBL7131545 | 0.81 | PHGDH (0.49) | LMNAALDH1A1KMT2AHTTPHGDH | |
| SCHEMBL7362762 | 0.81 | HTR6 (0.55) | ALDH1A1HTTPHGDHCA1CA2 | |
| SCHEMBL6797104 | 0.79 | POLB (0.54) | ALDH1A1MEN1KMT2AL3MBTL1PHGDH | |
| SCHEMBL1490842 | 0.79 | PHGDH (0.46) | LMNAATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693567-B | A kind of method for preparing arylsulfinate | 四川大学 | 2017-12-08 | — | — | CN | disclosed |
| WO-2004108094-A2 | SULFONAMIDE-SUBSTITUTED CHALCONE DERIVATIVES AND THEIR USE TO TREAT DISEASES | ATHEROGENICS, INC. (US) | 2004-12-16 | — | — | WO | disclosed |