Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 11/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454364 | 1.00 | NAAA (0.58) | NAAAPPARAHTR7FAAHFFAR1 | |
| SCHEMBL7412084 | 0.90 | NAAA (0.59) | NAAAPPARAFAAH | |
| SCHEMBL7115486 | 0.90 | NAAA (0.59) | NAAAPPARAFAAH | |
| SCHEMBL24252162 | 0.84 | NAAA (0.70) | NAAAPPARAFAAH | |
| SCHEMBL16401094 | 0.84 | NAAA (0.70) | NAAAPPARAFAAH | |
| SCHEMBL970410 | 0.84 | NAAA (0.70) | NAAAPPARAFAAH | |
| SCHEMBL13430381 | 0.83 | NAAA (0.72) | NAAAFAAH | |
| SCHEMBL7999516 | 0.83 | NAAA (0.72) | NAAAFAAH | |
| SCHEMBL7997611 | 0.83 | NAAA (0.72) | NAAAFAAH | |
| SCHEMBL7998820 | 0.83 | NAAA (0.72) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047665-B1 | MATRIX METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-10-22 | — | — | EP | disclosed |
| US-6350907-B1 | PEPTIDE ENZYME INHIBITORS | PFIZER INC | 2002-02-26 | — | — | US | disclosed |