Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 13/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115486 | 1.00 | NAAA (0.59) | NAAAFAAHPPARAHDAC1 | |
| SCHEMBL7454364 | 0.90 | NAAA (0.58) | NAAAFAAHPPARA | |
| SCHEMBL7115490 | 0.90 | NAAA (0.58) | NAAAFAAHPPARA | |
| SCHEMBL3437063 | 0.87 | NAAA (0.59) | NAAAFAAHPPARA | |
| SCHEMBL3437061 | 0.87 | NAAA (0.59) | NAAAFAAHPPARA | |
| SCHEMBL8994853 | 0.85 | NAAA (0.72) | NAAAFAAHPPARA | |
| SCHEMBL24252162 | 0.85 | NAAA (0.70) | NAAAFAAHPPARA | |
| SCHEMBL16401094 | 0.85 | NAAA (0.70) | NAAAFAAHPPARA | |
| SCHEMBL970410 | 0.85 | NAAA (0.70) | NAAAFAAHPPARA | |
| SCHEMBL7997026 | 0.84 | NAAA (0.74) | NAAAFAAHPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047665-A1 | MATRIX METALLOPROTEASE INHIBITORS | Pfizer Limited (GB) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999035124-A1 | MATRIX METALLOPROTEASE INHIBITORS | PFIZER LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |