Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363201 | 0.92 | MAPT (0.72) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL7115658 | 0.92 | MAPT (0.72) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL11515827 | 0.89 | MAPT (0.62) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL9906419 | 0.85 | FFAR4 (0.67) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL11210563 | 0.84 | ALDH3A1 (0.77) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL19041388 | 0.83 | MAPT (0.69) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL11694650 | 0.82 | ALDH3A1 (0.60) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL10764508 | 0.82 | MAPT (0.77) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL11648544 | 0.81 | MAPT (0.60) | MAPTTDP1POLBKMT2AMEN1 | |
| SCHEMBL31026210 | 0.81 | L3MBTL1 (0.68) | MAPTTDP1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019728-B1 | UTILISATION OF REACTIVE DYESTUFFS IN DYEING AND PRINTING BLENDED FABRICS POLYESTER/COTTON | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |