SCHEMBL7115753

SCHEMBL7115753

N#CC(C(=O)Nc1cc(Cl)ccc1Cl)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
L3MBTL1 Q9Y468 4/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
EPHX1 P07099 1/20 0.47
GRIK1 P39086 1/20 0.46
MAPT P10636 2/20 0.44
LMNA P02545 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
RAB9A P51151 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
KCNQ2 O43526 1/20 0.43
GAA P10253 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053734 0.82 ALDH1A1 (0.58) MEN1KMT2AL3MBTL1POLBALDH1A1
SCHEMBL7210943 0.81 NPC1 (0.54) MEN1KMT2AL3MBTL1HTTPOLB
SCHEMBL7058595 0.80 NPC1 (0.55) MEN1KMT2AHTTPOLBALDH1A1
SCHEMBL7052548 0.77 MEN1 (0.44) MEN1KMT2APOLBALDH1A1NPSR1
SCHEMBL28762296 0.75 POLB (0.65) MEN1KMT2AHTTPOLBALDH1A1
SCHEMBL7054064 0.74 ALDH1A1 (0.58) MEN1KMT2AHTTPOLBALDH1A1
SCHEMBL7059942 0.74 CYP1A2 (0.51) MEN1KMT2AHTTPOLBALDH1A1
SCHEMBL14254815 0.71 LMNA (0.62) MEN1KMT2AL3MBTL1MAPK1HTT
SCHEMBL7675947 0.71 GRIK1 (0.74) MEN1KMT2AMAPK1HTTPOLB
SCHEMBL11806292 0.71 CNR1 (0.45) MEN1KMT2AHTTALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6613931-B1 N-(3-chlorphenyl)-2-cyano-2-phenylacetamide BASF AKTIENGESELLSCHAFT (DE) 2003-09-02 US claimed
EP-1156715-B1 USE OF PHENYLACETAMIDES AS PLANT PROTECTIVES HAVING HERBICIDAL AND FUNGICIDAL EFFECT BASF AG (DE) 2003-05-07 EP claimed