Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | ALPG | P10696 | 2/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730977 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| Hydrochloric Acid SCHEMBL410676 | 0.83 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL8144459 | 0.80 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL28549268 | 0.80 | ALPG (0.63) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL29669994 | 0.80 | ALPG (0.63) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL7122140 | 0.79 | L3MBTL1 (0.58) | CYP19A1CYP11B1CYP11B2L3MBTL1SMN1; SMN2 | |
| SCHEMBL6400518 | 0.79 | ALPG (0.62) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL5523502 | 0.79 | ALPG (0.62) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL1718560 | 0.79 | ALPG (0.62) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL10852956 | 0.78 | KMT2A (0.69) | CYP19A1L3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |