Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76457 | 0.82 | EGFR (0.51) | SMN1; SMN2MEN1KMT2ACA12CA1 | |
| SCHEMBL1356022 | 0.80 | ALDH1A1 (0.53) | L3MBTL1CYP2D6CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL13489990 | 0.80 | KDM4E (0.53) | L3MBTL1CYP2D6CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL21076446 | 0.79 | MGLL (0.62) | ALDH1A1CYP19A1 | |
| SCHEMBL7115992 | 0.79 | CYP19A1 (0.72) | L3MBTL1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL5141415 | 0.77 | MEN1 (0.75) | L3MBTL1SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL76413 | 0.77 | MGLL (0.49) | L3MBTL1ALDH1A1CYP19A1 | |
| SCHEMBL5903400 | 0.76 | POLB (0.66) | L3MBTL1MEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL3260049 | 0.75 | CYP2D6 (0.95) | SMN1; SMN2MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL17675670 | 0.75 | MGLL (0.57) | SMN1; SMN2MEN1KMT2AALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |