Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 8/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7123033 | 0.86 | PARP1 (0.50) | KDM5APARP1KDM5BGRIN2DGRIN3B | |
| SCHEMBL7118635 | 0.76 | GRIN2D (0.53) | PARP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7114063 | 0.76 | GSK3B (0.47) | PARP1DAOFEN1ALDH1A1MAPT | |
| SCHEMBL7114911 | 0.74 | KDM4C (0.43) | KDM5APARP1KDM5B | |
| SCHEMBL13818064 | 0.71 | KDM5A (0.57) | KDM5APARP1KDM5BGRIN2DGRIN3B | |
| SCHEMBL31145968 | 0.71 | PARP1 (0.47) | KDM5APARP1KDM5BGRIN2DGRIN3B | |
| SCHEMBL1061771 | 0.71 | KDM5A (0.81) | KDM5APARP1KDM5BALDH1A1 | |
| SCHEMBL13708891 | 0.70 | PARP1 (0.55) | KDM5APARP1KDM5BGRIN2DGRIN3B | |
| SCHEMBL31145938 | 0.68 | KDM5A (0.44) | KDM5APARP1KDM5BDAOFEN1 | |
| SCHEMBL31146052 | 0.67 | PARP1 (0.42) | KDM5APARP1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069271-A1 | Quinolone compounds for use in treating viral infections | SMITHKLINE BEECHAM CORPORATION | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069271-A1 | Quinolone compounds for use in treating viral infections | IRF3, MAVS, NQO2 | KDM5A 2603/4885PARP1 854/4885KDM5B 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.