Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 8/20 | 0.57 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818061 | 0.88 | KDM5A (0.72) | KDM5APARP1KDM5BKDM4EGRIN2D | |
| SCHEMBL13708891 | 0.86 | PARP1 (0.55) | KDM5APARP1KDM5BKDM4EGRIN2D | |
| SCHEMBL25432233 | 0.85 | PARP1 (0.54) | KDM5APARP1KDM5BKDM4EDAO | |
| SCHEMBL31139875 | 0.85 | PARP1 (0.54) | KDM5APARP1KDM5BKDM4EDAO | |
| SCHEMBL1061771 | 0.81 | KDM5A (0.81) | KDM5APARP1KDM5BKDM4EALDH1A1 | |
| SCHEMBL2284247 | 0.78 | KDM4E (0.69) | KDM4EDAOALDH1A1GAAMAPT | |
| SCHEMBL7123033 | 0.76 | PARP1 (0.50) | KDM5APARP1KDM5BGRIN2DGRIN3B | |
| SCHEMBL31139842 | 0.76 | KDM5A (0.57) | KDM5APARP1KDM5BKDM4EDAO | |
| SCHEMBL25430812 | 0.76 | KDM5A (0.57) | KDM5APARP1KDM5BKDM4EDAO | |
| SCHEMBL10134606 | 0.73 | PARP1 (0.79) | KDM5APARP1KDM5BKDM4EDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20090143368-A1 | Use of Cinnamoyl Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | COL2A1, COL1A1, SMAD2 | KDM5A 1427/4885PARP1 3025/4885KDM5B 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.