SCHEMBL7116288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7462068	0.86	ESR1 (0.60)	ESR2ESR1ERAP1HSD17B3CA12
	SCHEMBL5088527	0.86	ESR1 (0.88)	ESR2ESR1ERAP1HSD17B3CA12
	SCHEMBL7125098	0.83	ESR1 (0.55)	ESR2ESR1ERAP1CA12CA9
	SCHEMBL31675804	0.83	ERAP1 (0.62)	ESR2ESR1ERAP1HSD17B3CA12
	SCHEMBL7164709	0.83	ERAP1 (0.62)	ESR2ESR1ERAP1HSD17B3CA12
	SCHEMBL7121802	0.82	ALDH1A1 (0.64)	ESR2ESR1NPC1KDM4EGAA
	SCHEMBL5109410	0.82	ESR1 (0.81)	ESR2ESR1ERAP1HSD17B3NPC1
	SCHEMBL5107909	0.82	ESR1 (0.67)	ESR2ESR1ERAP1HSD17B3NPC1
	SCHEMBL7120589	0.81	ESR2 (0.53)	ESR2ESR1ERAP1CA12CA9
	SCHEMBL13241261	0.81	ESR1 (1.00)	ESR2ESR1ERAP1HSD17B3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.