Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116386 | 0.80 | NPSR1 (0.42) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL143698 | 0.75 | NPSR1 (0.43) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL14311030 | 0.63 | NPSR1 (0.50) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL15312076 | 0.62 | NPSR1 (0.51) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL14286538 | 0.61 | NPSR1 (0.47) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL1029651 | 0.58 | RECQL (0.73) | KDM4ECYP2D6TSHRALDH1A1RECQL | |
| SCHEMBL149448 | 0.58 | KDR (0.51) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL13779362 | 0.58 | KDM4E (0.88) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL7116226 | 0.57 | NPSR1 (0.43) | NPSR1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL14847438 | 0.56 | KDM4E (0.55) | NPSR1KDM4EHTTCYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020276-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-03-13 | — | — | WO | disclosed |