SCHEMBL711798

SCHEMBL711798

O=C(O)c1cccc(C(=O)O)c1C(=O)O.O=C(O)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
ALOX15 P16050 1/20 0.63
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
AKR1C3 P42330 1/20 0.54
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
HMGB1 P09429 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
TSHR P16473 1/20 0.52
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23288 1.00 ALDH1A1 (0.63) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL10454889 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
Lithium SCHEMBL31339528 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL31253427 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL1535448 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
Water SCHEMBL713566 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
Hydrochloric Acid SCHEMBL1564027 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
Water SCHEMBL2004054 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL723062 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2
Hydrochloric Acid SCHEMBL3459326 0.97 ALDH1A1 (0.60) ALDH1A1ALOX15CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124705-B2 Macro-diacrylates and macro-polacrylates HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUER MATERIAL- UND KUESTENFORSCHUNG GMBH (DE) 2012-02-28 US disclosed
US-20110152072-A1 CORE-SHELL STRUCTURE, PROCESS FOR ITS PRODUCTION, AND EXHAUST GAS PURIFICATION CATALYST COMPRISING CORE-SHELL STRUCTURE TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2011-06-23 US disclosed
US-20110098418-A1 Additives For Detergents And Cleaning Agents CLARIANT FINANCE (BVI) LIMITED (VG) 2011-04-28 US disclosed