SCHEMBL711838

SCHEMBL711838

COC=C1C(=O)Oc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 1/20 0.47
TOP2A P11388 1/20 0.47
MIF P14174 1/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MCL1 Q07820 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ACHE P22303 1/20 0.42
LMNA P02545 2/20 0.40
STK17B O94768 5/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391221 1.00 TOP1 (0.47) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL30671756 1.00 TOP1 (0.47) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL30671755 1.00 TOP1 (0.47) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL29800479 1.00 TOP1 (0.47) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL16561703 1.00 TOP1 (0.47) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL14733192 1.00 TOP1 (0.47) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL8447771 0.81 ALDH1A1 (0.50) TOP1TOP2AMIFALDH1A1SMN1; SMN2
SCHEMBL8448279 0.78 TOP1 (0.38) TOP1ALDH1A1STK17BMAPTTDP1
SCHEMBL6813657 0.76 MIF (0.46) MIFALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL8445731 0.75 TOP1 (0.56) TOP1TOP2AMIFALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383864-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF ANHUI GUANGXIN AGROCHEMICAL CO., LTD. (CN) 2024-11-21 US claimed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 US claimed
EP-4317137-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF Anhui Guangxin Agrochemical Co., Ltd. (CN) 2024-02-07 EP claimed
WO-2023203574-A1 A PROCESS FOR PREPARATION OF AZOXYSTROBIN NACL INDUSTRIES LIMITED (IN) 2023-10-26 WO claimed
CN-116924997-A Preparation method of azoxystrobin intermediate 江苏剑牌农化股份有限公司 2023-10-24 CN claimed
US-20220185784-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL LTD (IN) 2022-06-16 US claimed
CN-114105918-A Preparation method of azoxystrobin intermediate 浙江工业大学 2022-03-01 CN claimed
EP-3956317-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL Limited (IN) 2022-02-23 EP claimed
CN-113767093-A Process for the preparation of azoxystrobin and intermediates thereof UPL有限公司 2021-12-07 CN claimed
CN-112174897-B Preparation method of azoxystrobin intermediate 广东石油化工学院 2021-08-03 CN claimed
CN-112174897-A Preparation method of azoxystrobin intermediate 广东石油化工学院 2021-01-05 CN claimed
WO-2020212919-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2020-10-22 WO claimed
US-20240383864-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF ANHUI GUANGXIN AGROCHEMICAL CO., LTD. (CN) 2024-11-21 US disclosed
CN-114957134-B Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2024-07-16 CN disclosed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 US disclosed
CN-118084805-A Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2024-05-28 CN disclosed
US-5760250-A CYCLIZATION, ALKENYLATION, ETHERIFICATION TO FORM FUNGICIDES ZENECA LIMITED (GB) 1998-06-02 US disclosed
WO-1998007707-A1 PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS ZENECA LIMITED (GB) 1998-02-26 WO disclosed
EP-0592435-A1 PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS ZENECA LIMITED (GB) 1994-04-20 EP disclosed
WO-1992008703-A1 PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383864-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF DNMT3L, AZI2, DNMT3A TOP1 1101/4885TOP2A 1764/4885MIF 127/4885
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof NISCH, STS, SNX2 TOP1 1029/4885TOP2A 1369/4885MIF 1773/4885
US-20220185784-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF NISCH, STS, SNX2 TOP1 1029/4885TOP2A 1369/4885MIF 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.