Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30671756 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL30671755 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL29800479 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL14733192 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL16561703 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL29391221 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL711838 | 0.81 | TOP1 (0.47) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL27442791 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTTMAPTRECQL | |
| SCHEMBL31686093 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL5174344 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940394-A1 | Chemical process | ZENECA LIMITED (GB) | 1999-09-08 | — | — | EP | disclosed |
| US-5847138-A | Chemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-12-08 | — | — | US | disclosed |
| US-5760250-A | CYCLIZATION, ALKENYLATION, ETHERIFICATION TO FORM FUNGICIDES | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |
| EP-0592435-A1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992008703-A1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-29 | — | — | WO | disclosed |