Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.66 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029060 | 0.90 | TOP2A (0.77) | TOP2ATOP2BF10PTAFR | |
| SCHEMBL11135067 | 0.83 | TOP2A (0.48) | TOP2ATOP2BNPC1GAAMEN1 | |
| SCHEMBL7561044 | 0.82 | TOP2A (0.47) | TOP2ATOP2BNPC1MEN1KMT2A | |
| SCHEMBL28407941 | 0.82 | TOP2A (0.54) | TOP2ATOP2BALDH1A1PTAFR | |
| SCHEMBL11134767 | 0.80 | MEN1 (0.47) | TOP2ATOP2BNPC1ALDH1A1MEN1 | |
| SCHEMBL11137789 | 0.80 | MEN1 (0.47) | TOP2ATOP2BNPC1ALDH1A1MEN1 | |
| SCHEMBL11134339 | 0.80 | ACHE (0.46) | TOP2ATOP2BNPC1GAAALDH1A1 | |
| SCHEMBL11135297 | 0.80 | CYP2D6 (0.45) | TOP2ATOP2BNPC1GAAKMT2A | |
| SCHEMBL549192 | 0.80 | TOP2A (1.00) | TOP2ATOP2BF10 | |
| SCHEMBL10365364 | 0.79 | TOP2A (0.47) | TOP2ATOP2BNPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030164222-A1 | Semi-solid primer compositions | LOCTITE (R&D) LIMITED (IE) | 2003-09-04 | — | — | US | disclosed |