Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137789 | 0.98 | MEN1 (0.47) | TOP2ATOP2BMEN1KMT2AHTT | |
| SCHEMBL11134767 | 0.98 | MEN1 (0.47) | TOP2ATOP2BMEN1KMT2AHTT | |
| SCHEMBL11135067 | 0.95 | TOP2A (0.48) | TOP2ATOP2BMEN1KMT2AHTT | |
| SCHEMBL11132142 | 0.84 | NPC1 (0.42) | TOP2ATOP2BHTTNPC1 | |
| SCHEMBL7118380 | 0.82 | TOP2A (0.66) | TOP2ATOP2BMEN1KMT2ANPC1 | |
| SCHEMBL11134339 | 0.80 | ACHE (0.46) | TOP2ATOP2BNPC1TSHR | |
| SCHEMBL20261843 | 0.80 | TOP2A (0.40) | TOP2ATOP2BNPC1 | |
| SCHEMBL10365364 | 0.79 | TOP2A (0.47) | TOP2ATOP2BMEN1KMT2ANPC1 | |
| SCHEMBL28088766 | 0.79 | TOP2A (0.47) | TOP2ATOP2BMEN1KMT2ANPC1 | |
| SCHEMBL9207860 | 0.79 | TOP2A (0.66) | TOP2ATOP2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192220-A1 | IMPROVED POLY(METH)ACRYLATE PLASTISOLS AND METHOD FOR PRODUCING THE SAME | Röhm GmbH & Co. KG (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000078865-A1 | IMPROVED POLY(METH)ACRYLATE PLASTISOLS AND METHOD FOR PRODUCING THE SAME | Röhm GmbH & Co. KG (DE) | 2000-12-28 | — | — | WO | disclosed |