SCHEMBL7118902

SCHEMBL7118902

F[B-](F)(F)F.NNC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.42
PTGS2 P35354 5/20 0.42
MGLL Q99685 4/20 0.41
FAAH O00519 2/20 0.41
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.39
HSP90AA1 P07900 1/20 0.39
TLR9 Q9NR96 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
XBP1 P17861 1/20 0.39
MAPK1 P28482 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GPR35 Q9HC97 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544989 0.93 PTGS1 (0.47) PTGS1PTGS2MGLLFAAHMAPT
Hydrochloric Acid SCHEMBL1827335 0.91 PTGS1 (0.46) PTGS1PTGS2MGLLFAAHMAPT
Trifluoroacetic Acid SCHEMBL19182964 0.85 PTGS1 (0.42) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL13224224 0.82 MGLL (0.54) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL20779330 0.81 PTGS1 (0.43) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL15432729 0.81 PTGS1 (0.61) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL2224805 0.79 PTGS1 (0.64) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL25586124 0.79 PTGS1 (0.64) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL1064498 0.79 PTGS1 (0.64) PTGS1PTGS2MGLLFAAHMAPT
Hydrochloric Acid SCHEMBL1829332 0.78 PTGS1 (0.62) PTGS1PTGS2MGLLFAAHMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528107-B2 Dissolving antimicrobial agent in solvent to form antimicrobial solution and contacting antimicrobial solution with portion of medical device under conditions effective for causing incorporation of agent into device SULZER CARBOMEDICS INC. 2003-03-04 US disclosed
US-20010003599-A1 METHOD FOR PRODUCING ANTIMICROBIAL ANTITHROMBOGENIC MEDICAL DEVICES CORCYM S.R.L. (IT) 2001-06-14 US disclosed
US-5053453-A Protein covalently bound to support material BAXTER INTERNATIONAL INC. (US) 1991-10-01 US disclosed