SCHEMBL544989

SCHEMBL544989

NNC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.47
PTGS2 P35354 6/20 0.47
MGLL Q99685 5/20 0.46
FAAH O00519 3/20 0.46
MAPT P10636 3/20 0.45
HTT P42858 2/20 0.45
LMNA P02545 2/20 0.45
HSP90AA1 P07900 1/20 0.45
TLR9 Q9NR96 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
XBP1 P17861 1/20 0.45
MAPK1 P28482 1/20 0.45
RECQL P46063 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
GPR35 Q9HC97 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1827335 0.98 PTGS1 (0.46) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL7118902 0.93 PTGS1 (0.42) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL13224224 0.89 MGLL (0.54) PTGS1PTGS2MGLLFAAHMAPT
Trifluoroacetic Acid SCHEMBL19182964 0.88 PTGS1 (0.42) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL20779330 0.87 PTGS1 (0.43) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL15432729 0.87 PTGS1 (0.61) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL2224805 0.85 PTGS1 (0.64) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL1064498 0.85 PTGS1 (0.64) PTGS1PTGS2MGLLFAAHMAPT
SCHEMBL25586124 0.85 PTGS1 (0.64) PTGS1PTGS2MGLLFAAHMAPT
Hydrochloric Acid SCHEMBL1829332 0.84 PTGS1 (0.62) PTGS1PTGS2MGLLFAAHMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 568 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260043066-A1 COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES THE UNIVERSITY OF CHICAGO (US) 2026-02-12 US claimed
WO-2024103007-A1 METHODS FOR DETECTING RNA AND MOLECULAR ANALYSIS IN THICK TISSUE SECTIONS THE JOHNS HOPKINS UNIVERSITY (US) 2024-05-16 WO claimed
US-11975077-B2 Guanylurea functionalized peptides and proteins for therapeutics THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2024-05-07 US claimed
CN-111505293-B Test strip for detecting variegated aspergillin and application thereof 北京望尔生物技术有限公司 2022-11-18 CN claimed
US-20220195072-A1 TARGETED ANTICOAGULANT NORTHWESTERN UNIVERSITY 2022-06-23 US claimed
US-11332880-B2 Modifying natural feathers for use in sporting goods DURABIRD (US) 2022-05-17 US claimed
US-20220001024-A1 GUANYLUREA FUNCTIONALIZED PEPTIDES AND PROTEINS FOR THERAPEUTICS THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2022-01-06 US claimed
US-20210214773-A1 COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES THE UNIVERSITY OF CHICAGO (US) 2021-07-15 US claimed
CN-108136254-B Natural feathers for use in sporting goods 杜拉博德有限责任公司 2021-06-04 CN claimed
EP-3790544-A1 COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES The University of Chicago (US) 2021-03-17 EP claimed
US-8420802-B2 Polymer support UNIVERSITY OF CAPE TOWN (ZA) 2013-04-16 US claimed
EP-2478049-A1 A POLYMER SUPPORT University of Cape Town (ZA) 2012-07-25 EP claimed
US-20120178916-A1 Polymer Support UNIVERSITY OF CAPE TOWN (ZA) 2012-07-12 US claimed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO claimed
US-20110142762-A1 Conjugates for medical imaging comprising carrier, targeting moiety and a contrast agent NOVOZYMES BIOPHARMA DK A/S (DK) 2011-06-16 US claimed
EP-1605979-B1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT UPPERTON LTD (GB) 2008-10-22 EP claimed
JP-2006518727-A 2006-08-17 JP claimed
US-20060171892-A1 Conjugates for medical imaging comprising carrier, targetting moiety and a contrast agent NOVOZYMES BIOPHARMA UK LIMITED (GB) 2006-08-03 US claimed
EP-1605979-A1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT Upperton Limited (GB) 2005-12-21 EP claimed
WO-2004071536-A1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT UPPERTON LIMITED (GB) 2004-08-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11975077-B2 Guanylurea functionalized peptides and proteins for therapeutics NPEPPS, SLC7A1, DNPEP PTGS1 2746/4885PTGS2 2984/4885MGLL 2781/4885
US-20260043066-A1 COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES RNMT, SMCHD1, PKLR PTGS1 2240/4885PTGS2 2726/4885MGLL 1183/4885
US-20220001024-A1 GUANYLUREA FUNCTIONALIZED PEPTIDES AND PROTEINS FOR THERAPEUTICS NPEPPS, SLC7A1, DNPEP PTGS1 2703/4885PTGS2 3016/4885MGLL 2910/4885
US-20210214773-A1 COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES RNMT, PHAX, RNGTT PTGS1 2423/4885PTGS2 2935/4885MGLL 2208/4885
US-20220195072-A1 TARGETED ANTICOAGULANT SERPINC1, PROC, PCSK6 PTGS1 3759/4885PTGS2 3380/4885MGLL 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.