Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 6/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 6/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 6/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 6/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176219 | 0.77 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2116067 | 0.76 | MEN1 (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5025802 | 0.75 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7128046 | 0.74 | CASP3 (0.47) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL1180003 | 0.73 | DYRK1A (0.58) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL22468024 | 0.72 | DYRK1A (0.65) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL12393158 | 0.72 | MEN1 (0.70) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL12297548 | 0.72 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL14006520 | 0.71 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL15207606 | 0.70 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | NPC1 310/4885RAB9A 1556/4885SMN1; SMN2 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.