Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468024 | 0.75 | DYRK1A (0.65) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL7119164 | 0.74 | NPC1 (0.60) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL7125157 | 0.74 | CCNA2 (0.35) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1180003 | 0.72 | DYRK1A (0.58) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL5025802 | 0.72 | NPC1 (0.68) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL3217871 | 0.70 | RAB9A (0.68) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL1176219 | 0.69 | NPC1 (0.59) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL14433291 | 0.69 | MAPT (0.55) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL8122841 | 0.69 | SMN1; SMN2 (0.66) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL27004484 | 0.68 | DYRK1A (0.62) | CASP3SENP8SENP7SENP6DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | CASP3 2654/4885SENP8 2965/4885SENP7 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.