Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498059 | 0.85 | THRB (0.49) | THRBTHRA | |
| SCHEMBL282132 | 0.83 | THRB (0.66) | THRBTHRA | |
| SCHEMBL13381631 | 0.82 | THRB (0.56) | THRBTHRA | |
| SCHEMBL12584355 | 0.81 | THRB (0.68) | THRBTHRA | |
| SCHEMBL12584183 | 0.80 | THRA (1.00) | THRBTHRA | |
| Sobetirome SCHEMBL29467327 | 0.79 | THRB (1.00) | THRBTHRA | |
| SCHEMBL7114750 | 0.79 | THRB (0.72) | THRBTHRA | |
| Sobetirome SCHEMBL282119 | 0.79 | THRB (1.00) | THRBTHRA | |
| SCHEMBL7372730 | 0.78 | THRB (0.80) | THRBTHRA | |
| SCHEMBL22095710 | 0.77 | THRB (0.91) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991618-B1 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2003-11-12 | — | — | EP | claimed |
| US-5883294-A | THYROID HORMONE AGONIST | THE REGEANTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-16 | — | — | US | disclosed |