Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778669 | 0.81 | MEN1 (0.43) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL3810061 | 0.81 | MEN1 (0.47) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL2083893 | 0.81 | PTK2 (0.38) | MEN1KMT2AMAPTPOLBNR4A1 | |
| SCHEMBL11443114 | 0.79 | MEN1 (0.42) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL28560254 | 0.79 | LTB4R (0.43) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL4773626 | 0.78 | KMT2A (0.41) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL11630922 | 0.78 | MEN1 (0.41) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL14039776 | 0.78 | KMT2A (0.41) | MEN1KMT2AMAPTPTPN2PTPRB | |
| SCHEMBL2081679 | 0.78 | HSP90AB1 (0.39) | MEN1KMT2AMAPTPOLBNR4A1 | |
| SCHEMBL11394536 | 0.78 | HNF4A (0.47) | MEN1KMT2APTPN2PTPN6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003212867-A | METHOD FOR PRODUCING 2,3-DISUBSTITUTED THIOPHENE DERIVATIVE | KURARAY CO LTD | 2003-07-30 | — | — | JP | disclosed |
| US-4560701-A | ANTIINFLAMMATORY, ANALGESIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-24 | — | — | US | disclosed |