SCHEMBL711979

SCHEMBL711979

O=C(OCC1c2ccccc2-c2ccccc21)N1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
KMT2A Q03164 5/20 0.48
FABP5 Q01469 3/20 0.47
FABP7 O15540 2/20 0.47
POLB P06746 2/20 0.46
EPHX2 P34913 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 2/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HSD17B10 Q99714 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31220527 1.00 TSHR (0.52) TSHRKMT2AFABP5FABP7POLB
SCHEMBL30276687 1.00 TSHR (0.52) TSHRKMT2AFABP5FABP7POLB
Hydrochloric Acid SCHEMBL28773949 0.98 TSHR (0.51) TSHRKMT2AFABP5FABP7POLB
SCHEMBL30824716 0.98 TSHR (0.50) TSHRKMT2AFABP5FABP7POLB
SCHEMBL30555288 0.98 TSHR (0.50) TSHRKMT2AFABP5FABP7POLB
SCHEMBL8222797 0.98 TSHR (0.50) TSHRKMT2AFABP5FABP7POLB
SCHEMBL22397770 0.92 POLB (0.52) TSHRKMT2AFABP5FABP7POLB
SCHEMBL13327274 0.92 POLB (0.52) TSHRKMT2AFABP5FABP7POLB
Trifluoroacetic Acid SCHEMBL28773939 0.91 TSHR (0.45) TSHRKMT2AFABP5FABP7POLB
Formic Acid SCHEMBL27577578 0.90 KMT2A (0.45) TSHRKMT2AFABP5FABP7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116298027-A Liquid chromatography detection method and application of genotoxic impurities 江苏诺泰澳赛诺生物制药股份有限公司 2023-06-23 CN claimed
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2026-05-07 US disclosed
US-20250262314-A1 MULTIFUNCTIONAL ANTIBODIES SYNAFFIX B.V. (NL) 2025-08-21 US disclosed
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 EP disclosed
EP-4582436-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BicycleTX Limited (GB) 2025-07-09 EP disclosed
EP-3727461-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LTD (GB) 2025-07-09 EP disclosed
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2025-06-26 US disclosed
EP-4362988-B1 ANTIMICROBIAL PEPTIDES AND THEIR USE UNIV MANCHESTER (GB) 2025-06-25 EP disclosed
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-06-05 US disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 EP disclosed
US-5708153-A PREPARING A LIBRARY AFFYMAX TECHNOLOGIES N.V. (GB) 1998-01-13 US disclosed
US-5670616-A CAPABLE OF BEING STAINED WITH CATIONIC CARBOCYANINE DYE EASTMAN KODAK COMPANY (US) 1997-09-23 US disclosed
EP-0773227-A1 Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides AFFYMAX TECHNOLOGIES N.V. (AN) 1997-05-14 EP disclosed
EP-0604552-B1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS AFFYMAX TECH NV (AN) 1997-02-12 EP disclosed
US-5580712-A CONTROLLING THE GRAIN MORPHOLOGY BY A CULTURE PRODUCT POLYPEPTIDES EASTMAN KODAK COMPANY (US) 1996-12-03 US disclosed
EP-0604552-A1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS. AFFYMAX TECH NV (AN) 1994-07-06 EP disclosed
EP-0604552-A4 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS. AFFYMAX TECH NV (AN) 1993-08-02 EP disclosed
EP-0537981-A2 Cleavage method for acyl thiohydantoins and use of the method in C-terminal peptide sequencing THE PERKIN-ELMER CORPORATION (US) 1993-04-21 EP disclosed
WO-1993006121-A1 METHOD OF SYNTHESIZING DIVERSE COLLECTIONS OF OLIGOMERS AFFYMAX TECHNOLOGIES N.V. (NL) 1993-04-01 WO disclosed
US-5185266-A Cleaving an alkylated thiohydantoin adduct from a peptide under anhydrous, acidic conditions and analyzing the side chain of the amino acid APPLIED BIOSYSTEMS, INC. (US) 1993-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS CDK1, CDK11A, CDK3 TSHR 3696/4885KMT2A 1352/4885FABP5 4471/4885
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 EPHA2, EPHB2, ERBB2 TSHR 801/4885KMT2A 1304/4885FABP5 2727/4885
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF BTD, CALCR, CA6 TSHR 3789/4885KMT2A 1230/4885FABP5 1053/4885
US-20250262314-A1 MULTIFUNCTIONAL ANTIBODIES C1S, APOL1, BTN3A1 TSHR 2191/4885KMT2A 3361/4885FABP5 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.