Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 17/20 | 0.49 |
| ▸ | F10 | P00742 | 8/20 | 0.49 |
| ▸ | F2 | P00734 | 14/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 13/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 13/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | PLAT | P00750 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060287 | 0.98 | PRSS1 (0.48) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7055160 | 0.93 | F10 (0.50) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7058024 | 0.91 | PRSS1 (0.50) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7058503 | 0.91 | F10 (0.48) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7058404 | 0.90 | PRSS1 (0.52) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7061680 | 0.90 | F10 (0.50) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7061531 | 0.89 | PRSS1 (0.51) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7057423 | 0.89 | F10 (0.48) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7062523 | 0.89 | F10 (0.49) | PRSS1F10F2PRSS2PRSS3 | |
| SCHEMBL7059958 | 0.89 | PRSS1 (0.46) | PRSS1F10F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166694-A1 | Glycinamides | MERCK PATENT GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166694-A1 | Glycinamides | F11, SERPINC1, F13A1 | PRSS1 115/4885F10 12/4885F2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.