Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130800 | 0.90 | CYP2C19 (0.56) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL9806370 | 0.90 | CYP2C19 (0.56) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL7011213 | 0.80 | ALDH1A1 (0.60) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL3848016 | 0.78 | ALDH1A1 (0.40) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL19130511 | 0.78 | CASR (0.47) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL3848041 | 0.78 | CASR (0.47) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL249404 | 0.78 | KMT2A (0.55) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 | |
| SCHEMBL17111064 | 0.78 | CYP2C19 (0.44) | CYP2C19CYP3A4TSHRALDH1A1HIF1A | |
| SCHEMBL19130465 | 0.77 | TSHR (0.44) | CYP2C19CYP3A4TSHRALDH1A1HIF1A | |
| SCHEMBL13714189 | 0.77 | ALDH1A1 (0.39) | CYP2C19CYP3A4TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660191-B1 | Prepared from corresponding 1,5-diethenylnaphthalene derivatives, and are well suited for the improved anionic polymerization of diene, vinylaromatic and/or (meth)acrylic monomers. | ELF ATOCHEM S.A. (FR) | 2003-12-09 | — | — | US | disclosed |
| EP-0673954-B1 | Difunctional initiators for anionic polymerisation derived from 1,5-diethenylnaphtalene and polymerisation process in which they are used | ATOCHEM ELF SA (FR) | 1999-04-28 | — | — | EP | disclosed |
| US-5744558-A | 1,5-diethenylnaphthalene compounds and bifunctional primers for anionic polymerization prepared therefrom | ELF ATOCHEM S.A. (FR) | 1998-04-28 | — | — | US | disclosed |
| EP-0673954-A1 | Difunctional initiators for anionic polymerisation derived from 1,5-diethenylnaphtalene and polymerisation process in which they are used | ELF ATOCHEM S.A. (FR) | 1995-09-27 | — | — | EP | disclosed |