Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130511 | 1.00 | CASR (0.47) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL11336791 | 0.88 | CASR (0.45) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL874172 | 0.86 | CASR (0.53) | CASRGABRA1GABRB2ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL27910256 | 0.84 | TRPA1 (0.42) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL2387148 | 0.81 | GABRA1 (0.43) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL11475054 | 0.80 | KMT2A (0.50) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL7011213 | 0.80 | ALDH1A1 (0.60) | ESR1ESR2ALDH1A1ALOX15TSHR | |
| SCHEMBL7030617 | 0.80 | CYP3A4 (0.44) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL813137 | 0.80 | CRHBP (0.55) | CASRGABRA1GABRB2ESR1ESR2 | |
| SCHEMBL7120000 | 0.78 | CYP2C19 (0.47) | ESR1ESR2ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196338-B2 | Chiral diamine compounds for the preparation of chiral alcohols and chiral amines | UNIVERSITY COLLEGE DUBLIN (IE) | 2019-02-05 | — | — | US | disclosed |
| US-9989849-B2 | Chemically amplified resist material and resist pattern-forming method | JSR CORPORATION (JP) | 2018-06-05 | — | — | US | disclosed |
| US-9939729-B2 | Resist pattern-forming method | JSR CORPORATION (JP) | 2018-04-10 | — | — | US | disclosed |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | UNIVERSITY COLLEGE DUBLIN (IE) | 2017-07-20 | — | — | US | disclosed |
| CN-105324401-B | Aromatic hydrocarbon formaldehyde resin, modified aromatic race hydrocarbon formaldehyde resin and epoxy resin and their manufacture method | 三菱瓦斯化学株式会社 | 2017-06-23 | — | — | CN | disclosed |
| US-20170131634-A1 | CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD | JSR CORPORATION (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20170075224-A1 | RESIST PATTERN-FORMING METHOD | JSR CORPORATION (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170075221-A1 | CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD | JSR CORPORATION (JP) | 2017-03-16 | — | — | US | disclosed |
| CN-105324401-A | Aromatic hydrocarbon formaldehyde resin, modified aromatic hydrocarbon formaldehyde resin, and epoxy resin, and method for producing said resins | MITSUBISHI GAS CHEMICAL CO | 2016-02-10 | — | — | CN | disclosed |
| US-7572927-B2 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572927-B2 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-7572927-B2 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-6265559-B1 | PEPTIDE NUCLEIC ACID SYNTHONS WHICH HAVE PROTECTING GROUPS WHICH ARE ORTHOGONAL; ALLOWS REMOVAL OF PROTECTING GROUPS UNDER MILD CONDITIONS; FOR PNA-DNA CHIMERAS | PERSEPTIVE BIOSYSTEMS, INC. | 2001-07-24 | — | — | US | disclosed |
| CN-1036919-C | Pyrazole condensed ring derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMA CO LTD (JP) | 1998-01-07 | — | — | CN | disclosed |
| CN-1089609-A | Pyrazole-fused ring derivatives, its manufacture method and male hormone inhibitor | OTSUKA PHARMA CO LTD (JP) | 1994-07-20 | — | — | CN | disclosed |
| US-5112851-A | Agricultural Fungicides | SANDOZ LTD. (CH) | 1992-05-12 | — | — | US | disclosed |
| US-4939148-A | Amine derivatives, processes for their production and their use | SANDOZ, LTD. (CH) | 1990-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | DDT, OXER1, OSTC | CASR 3286/4885GABRA1 1749/4885GABRB2 2820/4885 |
| US-10196338-B2 | Chiral diamine compounds for the preparation of chiral alcohols and chiral amines | ADH1C, ADH1A, ADH5 | CASR 4700/4885GABRA1 1468/4885GABRB2 1337/4885 |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | ADH1C, ADH1A, ADH5 | CASR 4690/4885GABRA1 1569/4885GABRB2 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.