Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066690 | 0.85 | TSHR (0.45) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL9462040 | 0.82 | ALDH1A1 (0.43) | TSHRALDH1A1THRBTDP1SMN1; SMN2 | |
| SCHEMBL6200579 | 0.80 | TSHR (0.53) | TSHRALDH1A1HPGDATMTHRB | |
| SCHEMBL17028805 | 0.80 | ALDH1A1 (0.59) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL18915848 | 0.80 | ALDH1A1 (0.59) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL5248798 | 0.79 | TSHR (0.52) | TSHRALDH1A1HPGDATMTHRB | |
| SCHEMBL7123449 | 0.79 | TSHR (0.52) | TSHRALDH1A1HPGDATMTHRB | |
| SCHEMBL7868028 | 0.78 | TSHR (0.45) | TSHRALDH1A1HPGDATMTHRB | |
| SCHEMBL12799675 | 0.78 | TSHR (0.39) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL6662257 | 0.77 | TSHR (0.50) | TSHRALDH1A1HPGDATMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083225-A1 | Organolipic substance | NATIONAL BANK OF CANADA (CA) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083225-A1 | Organolipic substance | SGMS2, SGMS1, CYP2S1 | TSHR 1902/4885ALDH1A1 919/4885HPGD 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.