Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590848 | 0.90 | TSHR (0.40) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5348407 | 0.89 | TSHR (0.44) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5342996 | 0.88 | KMT2A (0.53) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5344687 | 0.87 | TSHR (0.41) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5347557 | 0.87 | KMT2A (0.41) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5347583 | 0.86 | TSHR (0.41) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL4804356 | 0.86 | TSHR (0.57) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5347126 | 0.86 | KMT2A (0.41) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5345286 | 0.85 | TSHR (0.40) | KMT2ATSHRCYP2D6LMNAHSD17B10 | |
| SCHEMBL5346891 | 0.85 | KMT2A (0.40) | KMT2ATSHRCYP2D6LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | KMT2A 1595/4885TSHR 4818/4885CYP2D6 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.