Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778479 | 0.89 | ABL1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL24017192 | 0.86 | SHMT2 (0.40) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4224633 | 0.85 | BACE1 (0.51) | ALDH1A1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL24017167 | 0.84 | CYP1A2 (0.37) | CA1CA2CA7CA9CA12 | |
| Fluoride SCHEMBL14361225 | 0.83 | BACE1 (0.50) | ALDH1A1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL28299268 | 0.83 | CYP3A4 (0.55) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL18016419 | 0.83 | CYP11B1 (0.40) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL19478777 | 0.83 | L3MBTL1 (0.46) | MEN1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL30548757 | 0.82 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4992020 | 0.82 | CA1 (0.50) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835274-B1 | PROCESS FOR MAKING HYDROXY-SUBSTITUTED ETHYNYLATED BIPHENYLS | ALLIED SIGNAL INC (US) | 2000-04-26 | — | — | EP | claimed |
| US-5959157-A | Process for making hydroxy-substituted ethynylated biphenyl compounds | ALLIEDSIGNAL, INC. (US) | 1999-09-28 | — | — | US | claimed |
| EP-0835274-A1 | HYDROXY-SUBSTITUTED ETHYNYLATED BIPHENYLS | AlliedSignal Inc. (US) | 1998-04-15 | — | — | EP | claimed |
| WO-1997001594-A1 | HYDROXY-SUBSTITUTED ETHYNYLATED BIPHENYLS | ALLIEDSIGNAL INC. (US) | 1997-01-16 | — | — | WO | claimed |
| US-11183648-B2 | Polymers, their preparation and uses | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2021-11-23 | — | — | US | disclosed |
| US-20160343961-A1 | POLYMERS, THEIR PREPARATION AND USES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
| US-9419233-B2 | Polymers, their preparation and uses | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-08-16 | — | — | US | disclosed |
| US-20070248839-A1 | Dibenzosilol Polymers, Their Preparation and Uses | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
| US-20070248839-A1 | Dibenzosilol Polymers, Their Preparation and Uses | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
| JP-2003206289-A | FUNCTIONAL 9-METAL-SUBSTITUTED FLUORENE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | KANSAI TLO KK | 2003-07-22 | — | — | JP | disclosed |
| EP-0835275-B1 | IMPROVED POLY(ARYLENE ETHER) COMPOSITIONS AND THE METHOD FOR THEIR MANUFACTURE | ALLIED SIGNAL INC (US) | 2002-04-03 | — | — | EP | disclosed |
| US-RE37599-E1 | FROM PERFLUOROBENZENE OR FLUORINATED BENZENE POLYMERS AND AROMATIC DIOLS; USE IN COATING MICROELECTRONIC STRUCTURES, SUCH AS INTEGRATED CIRCUITS; LOW DIELECTRIC CONSTANT, LOW MOISTURE ABSORPTION, AND HIGH THERMAL STABILITY. | ALLIEDSIGNAL INC. | 2002-03-19 | — | — | US | disclosed |
| US-5986045-A | REACTION OF HALOARYLENE COMPOUND WITH DIPHENOL COMPOUND TO FORM POLYARYLENE ETHER | ALLIEDSIGNAL INC. (US) | 1999-11-16 | — | — | US | disclosed |
| US-5959157-A | Process for making hydroxy-substituted ethynylated biphenyl compounds | ALLIEDSIGNAL, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0835274-A1 | HYDROXY-SUBSTITUTED ETHYNYLATED BIPHENYLS | AlliedSignal Inc. (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0835275-A1 | IMPROVED POLY(ARYLENE ETHER) COMPOSITIONS AND THE METHOD FOR THEIR MANUFACTURE | AlliedSignal Inc. (US) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001594-A1 | HYDROXY-SUBSTITUTED ETHYNYLATED BIPHENYLS | ALLIEDSIGNAL INC. (US) | 1997-01-16 | — | — | WO | disclosed |
| WO-1997001593-A1 | IMPROVED POLY(ARYLENE ETHER) COMPOSITIONS AND THE METHOD FOR THEIR MANUFACTURE | ALLIEDSIGNAL INC. (US) | 1997-01-16 | — | — | WO | disclosed |
| US-4731442-A | High temperature solvent resistant amorphous thermoplastic phenylethynyl quinoxaline resin composition | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1988-03-15 | — | — | US | disclosed |
| US-4683340-A | Bis(benzilyloxy) compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1987-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160343961-A1 | POLYMERS, THEIR PREPARATION AND USES | PARG, PARP1, PCBP1 | CA1 4527/4885CA2 4858/4885CA7 3960/4885 |
| US-11183648-B2 | Polymers, their preparation and uses | PARG, PARP1, PCBP1 | CA1 4527/4885CA2 4858/4885CA7 3960/4885 |
| US-20070248839-A1 | Dibenzosilol Polymers, Their Preparation and Uses | PARG, PCBP1, RAD54L | CA1 4715/4885CA2 4879/4885CA7 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.