Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119104 | 0.84 | ALOX5 (0.60) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL7120273 | 0.83 | MAPT (0.63) | CYP1A1CYP1A2CYP1B1ABL1PDGFRB | |
| SCHEMBL7122127 | 0.83 | RAB9A (0.59) | CYP1A1CYP1A2CYP1B1ABL1PDGFRB | |
| SCHEMBL7117380 | 0.83 | ALOX5 (0.58) | CYP1A1CYP1A2CYP1B1ABL1PDGFRB | |
| SCHEMBL7129752 | 0.79 | PSEN1 (0.62) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL10072680 | 0.78 | MEN1 (0.61) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| Bromide SCHEMBL7129762 | 0.78 | PSEN1 (0.61) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL30723289 | 0.75 | ALOX5 (0.62) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL12298224 | 0.74 | MEN1 (0.69) | CYP1A1CYP1A2CYP1B1MEN1KMT2A | |
| SCHEMBL12298058 | 0.74 | ALOX5 (0.64) | CYP1A1CYP1A2CYP1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | CYP1A1 122/4885CYP1A2 25/4885CYP1B1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.