Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754301 | 0.81 | ITGB1 (0.38) | ITGB1ITGA4THRBMT-CO2MAPT | |
| SCHEMBL6579539 | 0.77 | ITGB1 (0.35) | ITGB1ITGA4THRBMT-CO2MAPT | |
| SCHEMBL5750208 | 0.75 | CTSL (0.46) | LMNAITGB1ITGA4RAB9ANPSR1 | |
| SCHEMBL6579542 | 0.74 | GCGR (0.35) | ITGB1ITGA4THRBMT-CO2NR1H4 | |
| SCHEMBL5751322 | 0.72 | ITGB1 (0.41) | ITGB1ITGA4MAPTNOS2NOS3 | |
| SCHEMBL1897805 | 0.72 | BACE1 (0.39) | LMNAITGB1ITGA4RAB9ANPSR1 | |
| SCHEMBL5751172 | 0.71 | BACE1 (0.38) | LMNAMAPTRAB9ANR1H4EPHX2 | |
| SCHEMBL5753208 | 0.69 | ITGB1 (0.38) | ITGB1ITGA4MAPTNOS2NOS3 | |
| SCHEMBL5750588 | 0.67 | MCHR1 (0.40) | LMNAMAPTRAB9ANR1H4EPHX2 | |
| SCHEMBL5752124 | 0.67 | BACE1 (0.38) | LMNAMAPTRAB9AGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |