Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.35 |
| ▸ | ADCY6 | O43306 | 4/20 | 0.35 |
| ▸ | ADCY3 | O60266 | 4/20 | 0.35 |
| ▸ | ADCY9 | O60503 | 4/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 4/20 | 0.35 |
| ▸ | ADCY7 | P51828 | 4/20 | 0.35 |
| ▸ | ADCY2 | Q08462 | 4/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 4/20 | 0.35 |
| ▸ | ADCY4 | Q8NFM4 | 4/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579539 | 0.97 | ITGB1 (0.35) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL5751437 | 0.93 | ITGB1 (0.37) | ITGB1ITGA4PTGER4 | |
| SCHEMBL5753208 | 0.89 | ITGB1 (0.38) | ITGB1ITGA4PTGER4 | |
| SCHEMBL5749899 | 0.89 | GCGR (0.38) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL5754301 | 0.83 | ITGB1 (0.38) | ITGB1ITGA4NR1H4PTGER4CNR1 | |
| SCHEMBL5751322 | 0.75 | ITGB1 (0.41) | ITGB1ITGA4PTGER4 | |
| SCHEMBL5753649 | 0.75 | NPSR1 (0.32) | — | |
| SCHEMBL7121405 | 0.74 | LMNA (0.39) | ITGB1ITGA4NR1H4EPHX2THRB | |
| SCHEMBL5751172 | 0.74 | BACE1 (0.38) | NR1H4EPHX2PTGER4BCHEBACE1 | |
| SCHEMBL1897805 | 0.73 | BACE1 (0.39) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | GCGR 570/4885ADCY6 3003/4885ADCY3 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.