Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335654 | 0.83 | TRPM8 (0.44) | TRPM8HSD11B1IDO1PIN1CA1 | |
| SCHEMBL15882481 | 0.83 | TRPM8 (0.44) | TRPM8HSD11B1IDO1PIN1CA1 | |
| SCHEMBL2461628 | 0.80 | TRPM8 (0.41) | TRPM8HSD11B1IDO1PIN1MTNR1A | |
| SCHEMBL28879772 | 0.79 | PDPK1 (0.46) | IDO1 | |
| SCHEMBL30481743 | 0.78 | IDO1 (0.42) | TRPM8IDO1PIN1CA1CA2 | |
| SCHEMBL31609333 | 0.78 | IDO1 (0.42) | TRPM8IDO1PIN1CA1CA2 | |
| SCHEMBL255287 | 0.78 | IDO1 (0.42) | TRPM8IDO1PIN1CA1CA2 | |
| SCHEMBL5965470 | 0.78 | IDO1 (0.42) | TRPM8IDO1PIN1CA1CA2 | |
| SCHEMBL27385115 | 0.77 | TRPM8 (0.43) | TRPM8 | |
| Propionamide SCHEMBL17335708 | 0.77 | MTNR1A (0.41) | TRPM8HSD11B1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874800-B1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | disclosed |